I just finished my second treatment of Yervoy (formally named Ipilimumab) and so far, have not experienced any side effects. Even though I was prepared for this possibility, I have mixed feelings about it. Diarrhea and rash are the most common side effects associated with this treatment, and even though both can be unpleasant and even dangerous (for example, diarrhea can lead to colitis), I also want to feel like this drug is working. Not feeling anything can be a blessing on one hand, but on the other, can lead to doubt and uncertainty. My doctor has told me that the side effects typically occur around the second and third treatment, and only being a few days out of the second one, I know I might be jumping the gun here. I just want to know that this drug is doing what it is intended to do, which is rev up my immune system to fight off the cancer. I'm hoping for the best!!!